Wassermann Test. As Wassermann tests proved to us years ago, the practical value of the test depends upon an appropriate balance of sensitivity and specificity coupled with the prevalence of the disease. From: Autoantibodies (Second Edition), 2007. Download as PDF. About this page.
One of the most widely used of all immunodiagnostic tests was that involving complement fixation, most notably the Wassermann test for syphilis first introduced in 1906. 58 This procedure was based upon two fundamental demonstrations from the laboratory of Jules Bordet: that complement would mediate the hemolysis of antibody-sensitized erythrocytes, 59 and that any antigen–antibody interaction would result in the nonspecific fixation of complement. 60 The presence of antibody in a patient ...
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The Wassermann Test, named after German physician and bacteriologist August von Wassermann, was developed in 1906. The exam involves testing patients’ blood samples for the syphilis bacterium antibody. Syphilis, an STD, is treatable in early stages through doses of penicillin.
The Wassermann test or Wassermann reaction ( WR) is an antibody test for syphilis, named after the bacteriologist August Paul von Wassermann, based on complement fixation. It was the first blood test for syphilis and the first in the nontreponemal test (NTT) category. Newer NTTs, such as the RPR and VDRL tests, have mostly replaced it.
Definition of Wassermann test. : a test for the detection of syphilis using the Wassermann reaction. — called also Was*ser*mann\ ˈwä- sər- mən. How to pronounce Wassermann test (audio) , ˈvä- . How to pronounce Wassermann test (audio) \.
Wassermann Test. (medicine), a method of diagnosing syphilis by means of a serological reaction. Named after A. von Wassermann. The Wassermann test is based on the ability of blood serum of syphilitic patients to form a complex with the appropriate antigen that absorbs complement (a component of normal serum); erythrocytes of sheep’s blood serve as the antigen, and the antibody is human blood serum.
Wassermann test - a complement-fixation test used in the diagnosis of syphilis. Synonym(s): Wassermann reaction